Benign Prostatic Hyperplasia (BPH)
Use the link below to share a full-text version of this article with your friends and colleagues. Learn more. Prostate volume is a major contributing factor to the rise of PSA level in the absence of adenocarcinoma [ 14 ].
Patients with a PSA level of 4. Patients with overt Prostatavolumen 32 cm3, acute urinary retention, previous prostatic surgery, previous medical treatment with finasteride or known prostate cancer were excluded. To avoid interobserver variance, only one staff member measured the prostatic Prostatavolumen 32 cm3 twiceand the mean value was calculated. Correlation coefficients were calculated using Pearson's method.
Linear regression analysis was used to assess the relationship between total gland and transition zone volume. There were significant differences in all variables except age between men with BPH and prostate Prostatavolumen 32 cm3. In the subgroup of 59 patients with small prostates, all variables in patients with BPH were significantly different from those in men with prostate cancer. For all patients the correlation coefficients were 0. In patients with small prostates the respective correlation coefficients were 0.
The correlation between transition zone volume and Prostatavolumen 32 cm3 gland volume was highly significant in all groups. The regression plot between total gland volume and transition zone volume. The correlation coefficients were 0.
For all patients, changing the PSAD threshold from 0. In patients with small prostates, using a PSAT threshold of 0. In patients with large prostates a PSAT threshold of 0. Prostate volume is reportedly an important contributing factor to the increase in PSA level in the absence of adenocarcinoma [ 14 ]. Using a PSAD threshold of 0. The reasons for the variable results for PSAD are not entirely clear, but factors limiting the accuracy of PSAD include the difficulty of measuring prostate volume accurately using TRUS possibly related to interobserver variability in measuring prostate volumethe variability of PSA level with ageing, and the variable distribution of glandular and stromal components in BPH [ 1417 ].
In the present study, a PSAD threshold of 0. First, a recent study determining the correlation between PSA and zonal volume showed that the best predictor of serum PSA level is not total prostate volume but transition zone volume, especially transition zone epithelial volume [ 19 ].
These authors also reported a clear correlation Prostatavolumen 32 cm3 age and the volume of the transition zone. The present study also showed the strong Prostatavolumen 32 cm3 between transition zone volume and total gland volume in all patients and in the two subgroups of prostate size; the correlation of PSA with transition zone volume was better than that with total gland volume.
The free uncomplexed form of PSA i. They suggested that there may be variations in PSA production by prostate cancer cells, but that BPH cells seem to have a particular level of production. Volume Prostatavolumen 32 cm3Issue 6. The full text of this article hosted at iucr. If you do not receive an email within 10 minutes, your email address may not be registered, and you may need to create a new Wiley Online Library account.
If the address matches an existing account you will receive an email with instructions to retrieve your username. BJU International. Free Access. Tools Request permission Export citation Add to favorites Track citation.
Share Give access Share full text access. Share full text access. Please review our Terms and Conditions of Use and check box below to share full-text version of article. Mean sd variable No. Figure 1 Open in figure viewer PowerPoint. PSA variable no. Figure 2 Open in figure viewer PowerPoint.
Discussion Prostate volume is reportedly an important contributing factor to the increase in PSA level in the absence of adenocarcinoma [ 14 ]. Acknowledgements This study was supported by Ministry of Education in Korea. Authors D. Yu, MD, Resident. Cheon, MD, Associate Professor. Lee, MD, Professor. Kim, MD, Professor. Koh, MD, Professor. Citing Literature. Volume 86Issue 6 October Pages Figures References Related Information. Close Figure Viewer. Prostatavolumen 32 cm3 All Figures Return to Figure.
Previous Figure Next Figure. Email or Customer ID. Forgot password? Old Password. New Password. Password Changed Successfully Your password has been changed. Returning user. Request Username Can't sign in? Prostatavolumen 32 cm3 your username?
Enter your Prostatavolumen 32 cm3 address below and Prostatavolumen 32 cm3 will send you your username.